Most of the key components of Fable wouldn't work - you'd arrive in town looking for a wife and a property only to find that every inch of land and woman-flesh is owned by some chinese conglomerate who're spamming the chat channels selling them off by the pound. So you take on a quest to save 7 chickens from a bunch of hobbes, and while you're bragging about how you're going to do it another player arrives back in town with 7 chickens and a basket of eggs under his arm. You log off for the night unfulfilled.
It might still be great - more in keeping with the original vision of Fable where you have a functioning world that exists independantly of your character : you arrive in town looking for a quest, some farmer asks you to save his daughter from a marauding troop of bandits, you head to the pub to have a bevvy first and check out the talent but as you're on your way there you see a bunch of heavily armed warriors running off in the direction of said bandits. Do you join them? Try to beat them to the girl? Try to beat them to a pulp? Or head to the pub and forget about her? And what if you get there and find that actually those bandits are another group of players, one of whom has wooed the farmer's daughter and eloped with her to the forest - do you take her back anyway? Pretend you didn't find her? Tell the farmer the truth? Tell him you didn't find her when really you slaughtered the other players and locked the daughter in your sex-dungeon? Fun for all the (Fritzl) family.
[center]I'm a nihilist, not a stylist, baby![center]