Fable:TLC has no native gamepad support. However this is a PC game so you can do whatever you want and use every possible input device you could think of. Wanna try using a Wii-Controller? Try finding an emulator for Windows.
The best input mapper for the 360 controller is XPadder. If you use this and configure it correctly, you can play Fable:TLC with the controller or any other Direct Input device I think.
"*** the World and drop the Neutron!"